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    Black Professionals In STEM
    Aug 29, 2020
      ·  Edited: Aug 29, 2020

    23andMe: Associate Scientist / Sr. Associate Scientist, Antibody Discovery

    in See What's New!

    South San Francisco, California, United States


    Who we are

    23andMe, the leading consumer genetics company, has accumulated a wealth of genotypic and phenotypic information from participants committed to improving human health through advances in genomics. Our Therapeutics team uses this data to discover and develop novel medicines to treat important diseases. The team currently has research programs across several therapeutic areas, including oncology, skin, respiratory and cardiovascular disease.

    We are seeking an outstanding Associate Scientist or Senior Associate Scientist who will contribute to the generation, discovery and characterization of antibodies across our Therapeutics portfolio.

    For more information about our Therapeutics team, please visit https://therapeutics.23andme.com/.

    What you’ll do

    • Handle aspects of a hybridoma workflow including performing fusions, clone picking and hybridoma antibody screening

    • Develop and establish novel methods to improve the current antibody discovery workflows

    • Antibody characterization including affinity and specificity determination, epitope binning and antibody sequencing

    • Collaborate with therapeutic leads to plan the strategy for antibody discovery

    • Interpret, record and present complex biological data

    • Communicate and collaborate with other colleagues effectively

    What you’ll bring

    • B.S. (+ min of 5 years’ research experience in industry or academia) or Master’s (+ min of 3 years’ research experience in industry or academia) in molecular biology, cell biology or related discipline

    • Strong technical expertise in molecular biology including DNA and RNA purification, diverse PCR methods (RT-PCR, RACE-PCR), Illumina Miseq library preparation, cloning

    • Adept in the characterization of protein-protein interaction using a variety of methods such as ELISA, FACS, Bio-Layer Interferometry (Octet) and/or surface plasmon resonance technology (Biacore)

    • Cell biology expertise including mammalian cell culture, transfection and running functional cell-based assays

    • Excellent communication skills with an ability to work both independently and in a team environment

    • Critical thinking with high degree of innovative and analytical skills

    Pluses:

    • Experience using hybridoma technology for antibody discovery including immunization, hybridoma fusion, clone picking and screening

    • Experience in applying single B-cell antibody technologies to antibody discovery ( e.g. single cell FACS sorting, microfluidics)

    Note:  Job title will be commensurate with experience and academic credentials.


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